We also investigated survival differences between cases with CD4+, CD8+, and CD68+ PT/IT ratio lower than 1 and cases with PT/IT ratio higher than or equal to 1; although without statistical significance, we observed a trend toward longer survival for cases with PT/IT ratio lower than 1 (named “hot” tumor immune microenvironment) (Supplementary Figure 2). The gene discussed is CD4; the disease is neoplasm.