DUSP9 and colorectal carcinoma: The results showed that in normal intestinal mucosa (n = 12), the DUSP9 promoter showed hypomethylation status (average methylation level was 15.4%), while in CRC (n = 12), the DUSP9 promoter showed hypermethylation status (average methylation level was 87.4%, P < 0.01) (Figure 2D).