As shown in Table 1, no significant differences were observed between mtDNA and gender, age, tumor location (skullbase vs. convexity), preoperative KPS score, tumor recurrent status, malignant transformation, extent of tumor resection, ER status, PR status, or Ki-67 labeling index (P > 0.05, Fisher's exact test). The gene discussed is ESR1; the disease is neoplasm.