The expression levels of genes ASS1 (arginosuccinate synthase 1), ASPA (aspartoacylase), GOT1 (glutamic-oxaloacetic transaminase 1), GAD1 (glutamate decarboxylase 1), GAD2 (glutamate decarboxylase 2) and ABAT in the metabolic subpathways 00250_1 (alanine, aspartate and glutamate metabolism), 00330_1 (arginine and proline metabolism), 00220_2 (arginine biosynthesis), and 00430_2 (taurine and hypotaurine metabolism) will affect the survival of GBM patients (32). Here, ASS1 is linked to glioblastoma.