Several biomarkers such as neutrophil gelatinase-associated lipocalin, urinary kidney injury molecule-1, IL-18, cystatin C, and lactate dehydrogenase have been proposed for AKI detection (Bonventre et al., 2010; Sen et al., 2015; Zager, Johnson & Becker, 2013). This evidence concerns the gene IL18 and acute kidney injury.