The results indicated that, at high concentrations (15 and 30 μM), 9za obviously elevated the apoptotic cell population, including showing apoptosis in the early stage (Annexin V +/PI -) and in late stage (Annexin V +/PI +) compared with the controls in NSCLC cells, but had no proapoptotic effect in MRC-5 cells (Figs. 4C–4D). Here, ANXA5 is linked to non-small cell lung carcinoma.