The IHC optical density score of MMP-2 in eutopic endometrium obtained from women with endometriosis was significantly higher (1.7783 ± 0.22 IHC optical density score) than in the eutopic endometrium obtained from women without endometriosis (1.41 ± 0.34, p = 0.0017). Here, MMP2 is linked to endometriosis.