Gene enrichment and ontology analysis have clarified involvement of NF-κB pathways in EBV(+)DLBCL compared with EBV(−) DLBCL of elderly cases that was in agreement with activation of NF-κB in EBV(+)DLBCL cell lines [64]. The gene discussed is NFKB1; the disease is diffuse large B-cell lymphoma.