The pro-inflammatory cytokine IL-1β, however, demonstrated significantly higher (1.6-fold) tissue concentrations in the lung of untreated, 2.5-fold increased concentrations in plasma of GENT-treated, and 2.2-fold higher concentrations in the spleen of GENT-treated female mice, and higher concentrations in the lung (1.7-fold) and spleen (1.7-fold) of (GENT + PTX)-treated male mice after 5.5 h of sepsis (Table 1). The gene discussed is IL1B; the disease is Sepsis.