Notably, CD39+ CD4+ as well as CD39+ γδ+ T cells of IBD patients showed a higher frequency of IL-10+ cells than their CD39– counterparts (CD4+: 3.988% vs 1.309%, p = 0.0102; γδ+: 2.847% vs 0.821%, p = 0.023) (Figure 4C). Here, ENTPD1 is linked to inflammatory bowel disease.