After 5 h of stimulation with PMA/Ionomycin, peripheral γδ+ T cells from IBD patients displayed significantly higher frequencies of IL-17A+ cells compared to peripheral γδ+ T cells from healthy donors (IBD 1.687% vs HD 0.666%, p = 0.0326) (Figure 4A), contrary to peripheral CD4+ or CD8+ T cells which displayed no differences in IL-17A expression (Figure 4A). Here, CD4 is linked to inflammatory bowel disease.