Using gene network analysis we previously demonstrated that MMP12 was one of the most highly expressed genes in MWCNT-exposed mice as well as in sarcoidosis patients, suggesting that MMP12 is a putative driver of granulomatous disease (detailed microarray information and raw data have been deposited in Gene Expression Omnibus1 [GSE 100500 and GSE75023 (13, 14)]. This evidence concerns the gene MMP12 and sarcoidosis.