The analysis of high-density oligonucleotide microarrays of PRV-infected RBCs of the Atlantic salmon (S. salar) also revealed a panel of genes with decreased expression compared with the pre-infection activity (19), including the mmp9, mmp13a, mmp14 (matrix metallopeptidases, MMP), ncf1 (neutrophil cytosol factor 1, NCF1), cyba (cytochrome b-245 alpha chain, also known as p22-phox), and others, such as the csf1ra (colony stimulating factor 1 receptor a) and csf3r (colony stimulating factor 3 receptor) which are involved in regulation of the inflammatory and immune processes. The gene discussed is CSF3R; the disease is infection.