We tried to compare the accuracy of this prediction with other possible metrics, such as the density of CD8+ T cells inside cancer-cell islands, the absolute numbers of CD8+ T cells and cancer cells, etc. In Figure 3, there exists an apparent overlap between the poor- and good-outcome group using the density of CD8+ T cells inside cancer-cell islands (Figure 3A) or the absolute numbers of CD8+ T cells and cancer cells (Figure 3B). The gene discussed is CD8A; the disease is cancer.