In rats, treatment with OXT lowered blood pressure in a hypertensive strain (Petersson and Uvnäs-Moberg, 2008), and prevented the occurrence of hypertension subsequent to hypoxic injury (Jameson et al., 2016), whereas hypertension induced by angiotensin-II was found to be exacerbated by OXT administration (Phie et al., 2015). The gene discussed is AGT; the disease is hypertensive disorder.