Particularly in our study, we found that calprotectin and lactoferrin are elevated in both HIV+ groups and, 17% of the INR and 5.6% of IR exceed the cut-off point of lactoferrin associated to gut inflammation (5.6 μg/g of stool); although, calprotectin concentrations were below the levels that are considered pathological in IBD [22–24]. The gene discussed is LTF; the disease is inflammatory bowel disease.