Since expression and nuclear localisation of PKM2 is regulated by epidermal growth factor (EGF) in U87 human glioblastoma cells,35 we tested the effects of EGF and also basic fibroblast growth factor (bFGF), a clinically important growth factor in CRCs, on PKM2 expression in CRC cells. The gene discussed is FGF2; the disease is colorectal carcinoma.