To examine the correlation of the expression of PKM2 and LDHA with Wnt/β-catenin signalling, we investigated their expression in small intestine tissue samples from WT and Apcmin/+ mice.33 PKM2 and LDHA levels were higher in tumours from Apcmin/+ mice compared with those from WT mice (Fig. 2b). Here, LDHA is linked to neoplasm.