These studies implicate several CSPGs, including neurocan (NCAN) and neuroglycan‐C and several matrix metalloproteinases (MMPs), such as MMP16, ‘a disintegrin and matrix metalloproteinases‐22’ (ADAM22), ADAMTSL3, ‘ADAMS with a thrombospondin domain 12’ (ADAMTS12) and ADAMTS‐16, (Bespalova et al., 2012; Dow et al., 2011; McGrath et al., 2013; Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014). This evidence concerns the gene MMP16 and schizophrenia.