While CTD primarily focuses on environmental chemical-related diseases (as opposed to infectious diseases), in March 2020, CTD launched a rapid response curation task force to text mine and curate breaking literature for COVID-19, resulting in new content from >350 scientific articles for associated CTD diseases (e.g. COVID-19, Coronavirus Infections and Severe Acute Respiratory Syndrome) key host genes (e.g. ACE2, TMPRSS4 and numerous cytokines), molecular mechanisms and phenotypes (e.g. viral life cycle and viral entry), and potential therapeutics. This evidence concerns the gene ACE2 and COVID-19.