Co-culturing DilC-stained (red) macrophages from 3 healthy donors with PKH67-stained (green) tumor cells (Glu- and Gal-CC) (Fig. 6i) resulted in less double-positive DilC+PKH67+ cells (indicative of macrophage-mediated phagocytosis) (Fig. 6j) for Gal-CC compared to Gluc-CC (Fig. 6k), indicating that macrophages are less able to detect and phagocytose Gal-CC than Gluc-CC, likely due to the overexpression of the “don’t eat me” CD47 receptor34 on the surface of Gal-CC (Fig. 6a, b). The gene discussed is CD47; the disease is neoplasm.