Interestingly, Asf1b KO mice present with a reduced red blood cell (RBC) count (8.62 versus 9.34 × 109 cells/ml; p < 0.05), an increased mean cell volume (MCV 49.15 versus 46.10 fL; p < 107), and an increased mean corpuscular hemoglobin (MCH 15.62 versus 14.80; p > 10−6), suggestive of compensatory anemia. This evidence concerns the gene ASF1B and anemia.