The AUC [95% CI] of the conventional T2D risk factors (model 2) predicting incident prediabetes/T2D without any cardiac stress biomarkers was 0.779 [0.750; 0.807] in the total study population and 0.796 [0.760; 0.832] in the subpopulation with available copeptin, CT-proET-1 and MR-proADM measurements. This evidence concerns the gene AVP and prediabetes syndrome.