Meanwhile, in an independent dataset of GSE123750, we found that TTC19 (P = 0.0078; Fig. 6k), TLR6 (P = 0.0086; Fig. 6l), and GNG12 (P = 0.045; Fig. 6m) were significantly expressed in severe asthma by comparison with mild-moderate asthma. The gene discussed is TLR6; the disease is asthma.