A successful use of non-residualizing radiohalogen labels was demonstrated earlier for ESPs such as HER2-binding Albumin-binding domain (ABD)-Derived Affinity ProTein 6 (ADAPT6) [29] and HER2-binding DARPins 9_29 and G3 [22,23], as well as for Ec1 for imaging of EpCAM expression in pancreatic and ovarian cancer models [30,31]. The gene discussed is ERBB2; the disease is ovarian cancer.