Concerning MEN1-related PAs, a recent study by Lines KE et al. [76] investigated the expression of miR-15a, miR-16-1, and let-7a in pituitary tumors from a mouse model of MEN1 tumorigenesis (i.e., Men1+/− mice), finding all three miRNAs to be significantly downregulated in MEN1 PAs compared to normal wild type pituitaries. The gene discussed is MEN1; the disease is pituitary tumor.