Moreover, luteolin diminishes the levels of miR-301-3p that targets caspase-8, ultimately sensitizing pancreatic cancer cells to the TNF superfamily member 10 (TNFSF10, also known as TNF-related apoptosis-inducing ligand (TRAIL)) [103] (Figure 2 and Table 3). Here, TNFSF10 is linked to familial pancreatic carcinoma.