The leptin–adiponectin ratio, after controlling for MetS, gender, and age, was associated with insulin (β = 0.389, p = 0.0001), HOMA-IR (β = 0.417, p = 0.0001), waist circumference (β = 0.579, p = 0.0001), BMI (β = 0.558, p = 0.0001), body fat percentage (β = 0.570, p = 0.001), total fat fold (β = 0.503, p = 0.0001), triglycerides (β = 0.300, p = 0.041), atherogenic index (β = 0.354, p = 0.008), and visceral fat level (β = 0.445, p = 0.004). Here, LEP is linked to metabolic syndrome.