IL6 and head and neck squamous cell carcinoma: We first investigated the whole patient cohort with regard to HNSCC-specific survival; CRP (hazard ratio (HR): 10.9, 95% confidence interval (CI): 2.5–46.5, Cox p-value 0.001) together with IL6 (HR: 11.7, 95% CI: 2.7–50.1, Cox p-value 0.001) showed significant predictions (Figure 3).