4F2hc-LAT1 and 4F2hc-LAT2 are expressed in different tissues, e.g., LAT1 (SLC7A5) in brain, ovary, testis, placenta, spleen, colon, blood-brain barrier, fetal liver, activated lymphocytes, tumor cells and LAT2 (SLC7A8) in small intestine, kidney, lung, heart, spleen, liver, brain, placenta, prostate, ovary, fetal liver, testis, skeletal muscle [2]. The gene discussed is LAT; the disease is neoplasm.