RNH1 and acute kidney injury: Analyzing the effect from RNase 1 and RNH1 serum levels on the probability of suffering AKI with a univariable logistic regression model for each point in time, RNase 1 showed a statistically significant effect 12 h after surgery (p = 0.0327, OR = 1.035) and 48 h after surgery (p = 0.0144, OR = 1.045, Figure 4A).