IMP3 and metastatic malignant neoplasm in the lymph nodes: They found that IMP3 expression in biopsy was significantly related to lymph node metastasis and stage and had a higher sensitivity than CT scan for lymph nodal metastases, suggesting that IMP3 expression in biopsy was of higher value in detecting lymph nodal metastases and could be used as a potential biomarker for the stage.