It is well known that (a) ethnic difference [140,141] between Asians and Europeans due to different body composition and metabolic profile [142], (b) matrix in which adiponectin is measured (plasma or serum) [134], (c) sex-dependent adiponectin levels [132,143], (d) body weight [137], (e) presence of metabolic syndrome [144], (f) onset of depressive event [107], and (g) the subtypes of depressive disorders [133,145,146,147] influence adiponectin levels. Here, ADIPOQ is linked to depressive disorder.