TNS4 and head and neck squamous cell carcinoma: Analysis of the Oncomine database [33] and both the Peng Head-Neck [34] and Ginos Head-Neck [35] datasets revealed that mRNA expression of CTEN was significantly higher in HNSCC tissue samples compared with normal tissue (fold change 1.691 (p = 0.014) and 1.894 (p < 0.0001), respectively; Figure 1a,b).