A study by Demidenko et al. has reported downregulation of eight (ABCA8, ABCB1, ABCC6, ABCC9, ABCC10, ABCD2, ABCG2, and ABCG4) and upregulation of two (ABCC4 and ABCG1) ABC transporters in prostate cancer compared to normal prostate tissue [93]. The gene discussed is ABCG2; the disease is prostate carcinoma.