PTK2 and cancer: Phenolic acids exhibit their anti-cancer properties by inducing apoptosis through the ASK-1, caspase-3, JNK-p38, and pRb pathways, suppressing cell cycle by p21, bcl2, and bcl-x upregulation and bim, bax, puma ans noxa downregulation, and reducing proliferation and angiogenesis by EGFR, MAPK, mTOR, PI3K/Akt, FAK/PTK2, and JAK/STAT upregulation.