IGF1R and lung carcinoma: Of relevant interest, miR-7-5p mimics were found to potentiate the gefitinib induced cytotoxicity in lung cancer, via inhibiting the epidermal growth factor receptor (EGFR) and insulin like growth factor 1 receptor (IGF1R) pathways [81], and other studies reported that inhibiting the EGFR signaling allowed autophagy to contribute to cell death [82].