The bile acid UDCA is used for treating several liver diseases such as hepatitis and biliary cirrhosis [122]; it can act as an antioxidant molecule, increasing the gene expression of glutamine-cysteine ligase, a key enzyme in GSH synthesis, and also enhancing Nrf2 expression and promoting its nuclear translocation in a model of cholestatic liver damage [123,124]. This evidence concerns the gene NFE2L2 and liver disorder.