In addition, several studies have reported that ILL induced apoptosis of triple-negative breast cancer cells via downregulation of signal transducer and activator of transcription 3 (STAT3) signaling via regulation of suppressor of cytokine signaling 3 and micro-RNA 30c [21] and increased expression levels of X-linked inhibitor of apoptosis and survivin in glioma cells [23]. This evidence concerns the gene STAT3 and glioma.