Analysis of inflammatory cytokines revealed that CRP, hs-CRP, IL-1β, IL-8, IL-10, and IL-6 expression levels were increased in severe pneumonia patients, and a higher proportion of the severe pneumonia population exhibited increased levels of CRP (100%), hs-CRP (92.3%), IL-6 (61.5%), and IL-10 (84.6%) compared with non-severe patients. This evidence concerns the gene CXCL8 and susceptibility to pneumonia measurement.