More specifically, BRAF rearrangement has been found in 75%–80% of cerebellar pilocytic astrocytomas, and BRAFV600E mutations have been identified in non-cerebellar regions of the brain.21 Most recently, a large analysis of LGG (which includes the spinal LGG analyzed in this study) demonstrated how molecular studies can be used to stratify these tumors into risk categories.18 To date, there are few studies specifically addressing the presence of KIAA1549–BRAF fusions and BRAFV600E point mutations in low-grade spinal cord tumors. Here, BRAF is linked to spinal cord neoplasm.