However, the Cdk1 mRNA expression was significantly higher in the 50 μg/ml NSE-treated oocytes than that the untreated in both control (1.47 ± 0.11 vs 1.03 ± 0.05, p = 0.037) and PCOS (1.17 ± 0.23 vs 0.56 ± 0.09, p = 0.012). Here, ENO2 is linked to polycystic ovary syndrome.