Furthermore, staining of FOXA1 has been shown to correlate with disease outcomes in prostate cancer patients, where even with high AR staining, low FOXA1 is associated with good prognoses, and strong FOXA1 staining correlates with poor prognoses19, indicating that FOXA1 may have an important effect on AR signaling and tumor progression. Here, FOXA1 is linked to Familial prostate cancer.