Raybaud et al. [ 24] reported Epstein - Barr virus (EBV) infection in 74% of OLP with higher rate in erosive type and presence of higher number of plasma cells in OLP lesions infected with EBV.Nearly all EBV+ cells detected in OLP lesions were CD138+ plasma cells and more rarely CD20+ B cells, this means that plasma cells can play the role of host to EBV,and help the amplification of the virus particle. Here, SDC1 is linked to Epstein-Barr virus infection.