Furthermore, recent studies have also reported that PYCR1 is up-regulated in human cancers, and thus promote the progression of cancers including non-small-cell lung cancer (Wang et al., 2019), prostate cancer (Zeng et al., 2017), and hepatocellular cancer (Zhuang et al., 2019), among others. The gene discussed is PYCR1; the disease is hepatocellular carcinoma.