Suriano et al. in 2005 conducted a CDH1 genetic mutational analysis, where a family history of lobular breast carcinoma was found with a similar DGC causing CDH1 mutation and another individual who presented with both DGC and ILBC with the same mutation [35]. Xie et al. published a case series where he studied two families which presented with six ILBC but no history of DGC, showing similar mutational characteristics of inactivation of CDH1 gene shown by other studies, and Corso et al. in 2016 also published an article showing similar findings [36,37]. This evidence concerns the gene CDH1 and breast lobular carcinoma.