RB1 and cancer: Finally, CNV-mQTLs were found to be associated with CpG island methylation of genes frequently altered in cancer, e.g., PTEN, RB1, ERBB2, WNT1, WNT4, WNT11, MAPK15, and MAPK6. These data show that identifying the genes associated with CNV-mQTLs may lead to a better understanding and interpretation of GWAS data.