VTCN1 and pachyonychia congenita: However, we did not observe a significant upregulation of PVRL2 (Figure 3(b)), CSF1R (Figure 3(c)), TGFBR1 (Figure 3(d)), VTCN1 (Figure 3(e)), LGALS9 (Figure 3(f)), IL10RB (Figure 3(g)), KDR (Figure 3(h)), and IDO1 (Figure 3(i)) in advanced grades of PC samples.