The present study analyzed the expression pattern of 23 immunoinhibitors in PC using TCGA database, including CD160, CD244, KIR2DL1, KIR2DL3, BTLA, CSF1R, HAVCR2, TIGIT, LAG3, PDCD1, VTCN1, PDCD1LG2, LGALS9, CD96, TGFBR1, TGFB1, CTLA4, ADORA2A, PVRL2, IL10, IDO1, IL10RB, and KDR. This evidence concerns the gene KIR2DL3 and pachyonychia congenita.