The present study analyzed the expression pattern of 23 immunoinhibitors in PC using TCGA database, including CD160, CD244, KIR2DL1, KIR2DL3, BTLA, CSF1R, HAVCR2, TIGIT, LAG3, PDCD1, VTCN1, PDCD1LG2, LGALS9, CD96, TGFBR1, TGFB1, CTLA4, ADORA2A, PVRL2, IL10, IDO1, IL10RB, and KDR. The gene discussed is PDCD1; the disease is pachyonychia congenita.