In this study, we analyzed the expression pattern of 23 immunoinhibitors in PC using TCGA database and found that IDO1, CSF1R, VTCN1, KDR, LGALS9, TGFBR1, TGFB1, IL10RB, and PVRL2 were highly expressed in PC tissues. The gene discussed is LGALS9; the disease is pachyonychia congenita.