TP53 and cancer: Triterpenoid 1, xanthone 5, and doxorubicin displayed cytotoxic effects towards the 9 tested cancer cell lines with IC50 values ranging from 14.44 μM (against CCRF-CEM cells) to 44.20 μM (against the resistant HCT116 (p53−/−) cells) for 1, from 38.46 μM (against CEM/ADR5000 cells) to 112.27 μM (against HCT116 (p53−/−) cells) for 5, and from 0.02 μM (against CCRF-CEM cells) to 122.96 μM (against CEM/ADR5000 cells) for doxorubicin (Table 2).