In addition, the positive likelihood ratio (LH) was 6.55 which indicates that this test can increase the index of suspicion for confirming the PCOS diagnosis by 35–40%, while its negative LH (0.29) indicates it has 25–30% ability to exclude the diagnosis of PCOS; this was in agreement with a recent Turkish study in 2018 with kisspeptin levels in a normal ovarian reserve which were 4.65 ± 2.16 ng/mL, and 5.76 ± 2.11 in those with a high ovarian reserve [12]. This evidence concerns the gene PLOD1 and polycystic ovary syndrome.