METTL3 and lung carcinoma: In lung cancers, METTL3 was found to selectively promote the translation of mRNAs containing the m6A peaks around the stop codons, such as mRNA transcripts of the oncogenes EGFR and DNMT3A, and to increase the expression of the oncoproteins, thereby facilitating the proliferation and invasion of the tumor cells (Lin et al., 2016).