TRAF3 and neoplasm: Immunohistochemical staining showed that, compared with the negative control group, cytoplasmic TRAF3 tumor staining in the overexpression group was decreased and the number of stained cells was clearly significantly reduced; while in the inhibition group, cytoplasmic TRAF3 tumor staining was increased and the number of stained cells significantly increased (Additional file 5: Figure S5A, S5B).